Duodeno-jejunal bypass restores β-cell hypersecretion and islet hypertrophy in western diet obese rats.
Mariana Carla MendesMaria Lúcia BonfleurRosane Aparecida RibeiroCamila LubaczeuskiAna Flavia Justino FêoRodrigo VargasEverardo Magalhães CarneiroAntonio Carlos BoscheroAllan Cezar Faria AraujoSandra Lucinei BalboPublished in: Endocrine (2018)
DJB surgery improves fasting glycemia and insulin action in skeletal muscle. Better endocrine pancreatic morphofunction was associated, at least in part, with the regulation of the cholinergic and cAMP pathways, and improvements in syntaxin-1 islet protein content induced by DJB.
Keyphrases
- skeletal muscle
- weight loss
- type diabetes
- insulin resistance
- minimally invasive
- adipose tissue
- binding protein
- single cell
- coronary artery bypass
- metabolic syndrome
- cell therapy
- physical activity
- blood glucose
- south africa
- bariatric surgery
- surgical site infection
- obese patients
- stem cells
- blood pressure
- mesenchymal stem cells
- bone marrow
- protein kinase