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Effect of retinol and α-tocopherol supplementation on photoreceptor and retinal ganglion cell apoptosis in diabetic rats model.

Andi Muhammad IchsanAgussalim BukhariSubehan LalloUpik Anderiani MiskadAndi Afdal DzuhryItzar Chaidir IslamHabibah Setyawati Muhiddin
Published in: International journal of retina and vitreous (2022)
In diabetic rats, retinol and α-tocopherol compounds maintained densities and prevented photoreceptor and RGC death. However, α-tocopherol was more promising than retinol or combinations in the prevention of retinal cells apoptosis.
Keyphrases
  • diabetic rats
  • oxidative stress
  • induced apoptosis
  • cell cycle arrest
  • cell death
  • endoplasmic reticulum stress
  • cell proliferation
  • optical coherence tomography
  • pi k akt
  • diabetic retinopathy
  • signaling pathway