Haemodynamic effects of initial combination therapy in pulmonary arterial hypertension: a systematic review and meta-analysis.

Ioannis T FarmakisElena VranaSophia-Anastasia MouratoglouStefanos ZafeiropoulosStavros ZanosGeorge Giannakoulas

Published in: ERJ open research (2022)

Initial combination therapy leads to remarkable haemodynamic amelioration. Parenteral prostanoids should be considered early, especially in more severely affected patients, to enable right ventricular reverse remodelling.

Keyphrases

combination therapy
pulmonary arterial hypertension
end stage renal disease
pulmonary artery
ejection fraction
pulmonary hypertension
newly diagnosed
chronic kidney disease
prognostic factors
coronary artery
patient reported outcomes