Association of patients' sex with treatment outcomes after intravesical bacillus Calmette-Guérin immunotherapy for T1G3/HG bladder cancer.
David d'AndreaFrancesco SoriaAnne J GrotenhuisEugene K ChaNuria MalatsSavino Di StasiSteven JoniauTommaso CaiBas W G van RhijnJaques IraniJeffrey KarnesJohn VarkarakisJack BanielJoan PalouMarek BabjukMartin SpahnPeter ArdeltRenzo ColomboVincenzo SerrettaGuido DalbagniPaolo GonteroRiccardo BartolettiStephane LarréPer-Uno MalmstromRichard SylvesterShahrokh F ShariatPublished in: World journal of urology (2021)
Our analysis generates the hypothesis of a differential response to BCG between males and females if not adequately treated. Further studies should focus on sex-based differences in innate and adaptive immune system and their association with BCG response.