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The prometastatic relevance of tumor-infiltrating B lymphocytes in laryngeal squamous cell carcinoma.

Francesco MissaleMattia BugattiFilippo MarchiGiulio E MandelliMaria BruniGiulia PalmeriniMatilde MontiAnna M BozzolaGiorgio ArenaLuca GuastiniMaurizio BoggioGiampiero ParrinelloGiorgio PerettiWilliam Vermi
Published in: Clinical & translational immunology (2023)
The identification of regulatory B cells in the context of LSCC, along with the activation of the TGFβ pathway, could provide the basis for new trials investigating the efficacy of already available molecules targeting the TGFβ pathway in the treatment of LSCC.
Keyphrases
  • squamous cell carcinoma
  • transforming growth factor
  • transcription factor
  • peripheral blood
  • cancer therapy
  • epithelial mesenchymal transition
  • locally advanced
  • radiation therapy
  • drug delivery
  • signaling pathway