Effects of Levodopa-Carbidopa Intestinal Gel Compared with Optimized Medical Treatment on Nonmotor Symptoms in Advanced Parkinson's Disease: INSIGHTS Study.

Sun Ju Chung Matilde Calopa Maria Gabriella Ceravolo Nicola Tambasco Angelo Antonini Kallol Ray Chaudhuri Weining Z Robieson Olga Sánchez-Soliño Cindy ZadikoffMan JinLuigi M Barbato

Published in: Parkinson's disease (2022)

There were no significant differences between LCIG versus OMT in NMSS or PDSS-2; both LCIG and OMT groups significantly improved from baseline. AEs were consistent with the known safety profile.

Keyphrases

parkinson disease
healthcare
deep brain stimulation
depressive symptoms
sleep quality
combination therapy