Nomogram to Predict Distant Metastasis Probability for Pathological Complete Response Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy.
Ting JiangShuang LiuXiaojun WuXiaoqing LiuWeizhan LiShanfei YangPeiqiang CaiShaoyan XiZhi-Fan ZengYuanhong GaoGong ChenWeiwei XiaoPublished in: Cancer management and research (2021)
The nomogram model, including age, pre-operative CEA, pre-treatment CEA and distance to anal verge, predicted the probability of DM among LARC patients achieving pCR after NACRT. The effects of ACT were not seen in different subgroups, while closer clinical follow-up may have greater contribution to pCR patients in the first 2 years, especially for patients with relatively higher risk to develop DM. It is suggested that timely active treatment can bring survival benefit for pCR patients developing DM after NACRT.