Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy.
Bjarke FeenstraPeter BagerXueping LiuHenrik HjalgrimEllen A NohrDavid M HougaardFrank GellerMads MelbyePublished in: Journal of medical genetics (2016)
We identified and replicated a genetic association at 22q12.2 with tonsillectomy. Further functional investigation is required to illuminate whether the molecular mechanisms underlying the genetic association involve general lymphoid hyper-reaction throughout the mucosa-associated lymphoid tissue system.