The NF-κB signalling pathway and TM7SF3 contribute to liver fibrosis caused by secreted phospholipase A2 of Clonorchis sinensis.

Yin-Juan WuQing HeMei ShangYing-Xuan YinYe LiXue DuXue-Rong Li

Published in: Parasites & vectors (2021)

The NF-ΚB signalling pathway is involved in the activation of HSCs by CssPLA2. TM7SF3, the receptor of CssPLA2, plays important roles in liver fibrosis caused by CssPLA2.

Keyphrases

liver fibrosis
signaling pathway
lps induced
pi k akt
nuclear factor
oxidative stress
inflammatory response
immune response
cell proliferation
binding protein