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Participation of Monocarboxylate Transporter 8, But Not P-Glycoprotein, in Carrier-Mediated Cerebral Elimination of Phenytoin across the Blood-Brain Barrier.

Ryuta JomuraShin-Ichi AkanumaBjörn BauerYukiko YoshidaYoshiyuki KuboKen-Ichi Hosoya
Published in: Pharmaceutical research (2021)
Our data suggest that MCT8 at the BBB participates in phenytoin efflux transport from the brain to the blood.
Keyphrases
  • cerebral ischemia
  • blood brain barrier
  • subarachnoid hemorrhage
  • electronic health record
  • resting state
  • white matter
  • physical activity
  • big data
  • functional connectivity
  • multiple sclerosis
  • artificial intelligence