The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle.

Mayra Furlan-MagarilMasami Ando-KuriRodrigo G Arzate-MejíaJörg MorfJonathan CairnsAbraham Román-FigueroaLuis Tenorio-HernándezA César Poot-HernándezSimon AndrewsCsilla VárnaiBoo VirkSteven W WingettPeter Fraser

Published in: Genome biology (2021)

Our results identify chromatin conformation dynamics at different scales that parallel oscillatory gene expression and characterize the repertoire of regulatory elements that control circadian gene transcription through rhythmic or stable chromatin configurations.

Keyphrases

gene expression
transcription factor
genome wide
dna methylation
genome wide identification
copy number
high frequency
dna damage
crystal structure
high throughput sequencing
genome wide analysis