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The transcription factor STAT6 plays a critical role in promoting beta cell viability and is depleted in islets of individuals with type 1 diabetes.

Kaiyven A LeslieMark A RussellKazuto TaniguchiSarah J RichardsonNoel G Morgan
Published in: Diabetologia (2018)
Selective loss of STAT6 may contribute to beta cell demise during the progression of type 1 diabetes.
Keyphrases
  • transcription factor
  • cell proliferation
  • single cell
  • cell therapy
  • dna binding
  • stem cells
  • bone marrow