The transcription factor STAT6 plays a critical role in promoting beta cell viability and is depleted in islets of individuals with type 1 diabetes.
Kaiyven A LeslieMark A RussellKazuto TaniguchiSarah J RichardsonNoel G MorganPublished in: Diabetologia (2018)
Selective loss of STAT6 may contribute to beta cell demise during the progression of type 1 diabetes.