Locally recurrent rectal cancer: Oncological outcomes for patients with a pathological complete response after neoadjuvant therapy.
Stefi NordkampFloor PiqeurKim van den BergJip L TolenaarIrene E G van HellemondGeert-Jan CreemersMark RoefGesina van LijnschotenJeltsje S CnossenGrard A P NieuwenhuijzenJohanne G BloemenLiën CoolenJoost NederendHeike M U PeulenHarm J T RuttenJacobus W A BurgerPublished in: The British journal of surgery (2023)
This study showed that patients with a pCR have superior oncological outcomes to those without a pCR. It may therefore be safe to consider a watch-and-wait approach in highly selected patients, potentially improving quality of life by omitting extensive surgical procedures without compromising oncological outcomes.
Keyphrases
- rectal cancer
- locally advanced
- end stage renal disease
- newly diagnosed
- radical prostatectomy
- ejection fraction
- chronic kidney disease
- prostate cancer
- robot assisted
- stem cells
- lymph node
- squamous cell carcinoma
- prognostic factors
- skeletal muscle
- weight loss
- peritoneal dialysis
- metabolic syndrome
- glycemic control
- patient reported outcomes