Bidirectional Enhancement of Cell Proliferation Between Iron Oxide Nanoparticle-Labeled Mesenchymal Stem Cells and Choroid Plexus in a Cell-Based Therapy Model of Ischemic Stroke.
Menq-Rong WuChia-Hsun LeeJong-Kai HsiaoPublished in: International journal of nanomedicine (2020)
Crosstalk with the CP enhances MSC proliferation and migration in a transwell assay. Moreover, MRI reveals MSC migration towards the CP in an ischemic stroke model. The secreted factors resulting from this interaction have therapeutic potential for promoting functional recovery in the brain after ischemic stroke.
Keyphrases
- iron oxide
- mesenchymal stem cells
- atrial fibrillation
- cell proliferation
- cell therapy
- magnetic resonance imaging
- single cell
- white matter
- umbilical cord
- cell cycle
- resting state
- bone marrow
- ultrasound guided
- computed tomography
- magnetic resonance
- pi k akt
- signaling pathway
- multiple sclerosis
- functional connectivity
- pet ct