A Validated LC-MS/MS Assay for the Quantification of Cholate Isotopes in Human Serum.

Steve M HelmkeMichael P McRaeUwe ChristiansTouraj ShokatiGregory T Everson

Published in: The journal of applied laboratory medicine (2024)

The method validation studies described herein established the performance characteristics in terms of accuracy, precision, analytical sensitivity, analytical specificity, reportable ranges, and reference intervals of the LC-MS/MS cholate assay and DuO test.

Keyphrases

high throughput
liquid chromatography
mass spectrometry
single cell
structural basis