Pooled genome wide association detects association upstream of FCRL3 with Graves' disease.
Jwu Jin KhongKathryn P BurdonYi LuKate LaurieLefta LeonardosPaul N BairdSrujana SahebjadaJohn P WalshAdam GajdatsyPeter R EbelingPeter Shane HamblinRosemary WongSimon P ForehanSpiros FourlanosAnthony P RobertsMatthew DoogueDinesh SelvaGrant W MontgomeryStuart MacgregorJamie E CraigPublished in: BMC genomics (2016)
Pooled genome wide association study identified a genetic variant upstream of FCRL3 as a susceptibility locus for Graves' disease in addition to those identified in the Major Histo-compatibility Complex. A second locus downstream of DPYSL2 is potentially a novel genetic variant in Graves' disease that requires further confirmation.