Preventive effect of tertiary lymphoid structures on lymph node metastasis of lung adenocarcinoma.

Sho WakasuTetsuzo TagawaNaoki HaratakeFumihiko KinoshitaYuka OkuYuki OnoTomoyoshi TakenakaYoshinao OdaMototsugu ShimokawaMasaki Mori

Published in: Cancer immunology, immunotherapy : CII (2023)

Mature TLSs were associated with an increased number of cytotoxic lymphocytes in draining LNs, a lower frequency of LN metastasis, and favorable outcomes. Mature TLSs may support antitumor immunity by lymphocyte activation.

Keyphrases

lymph node metastasis
peripheral blood
squamous cell carcinoma
papillary thyroid
high resolution
type diabetes
metabolic syndrome
mass spectrometry
glycemic control
anti inflammatory