Neuropsychological Phenotypes in Pediatric Temporal Lobe Epilepsy.

William A SchraegleNancy L NussbaumRosario C DeLeonJeffrey B Titus

Published in: Journal of the International Neuropsychological Society : JINS (2021)

Children with TLE present with distinct cognitive phenotypes ranging from average performance to global impairment. Results partially support previous hypotheses highlighting the cumulative neurobiological burden on the developing brain in the context of chronic epilepsy and provide a preliminary framework for the cognitive domains most vulnerable to the TLE disease process.

Keyphrases

temporal lobe epilepsy
young adults
white matter
mild cognitive impairment
risk factors
multiple sclerosis
brain injury