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Higher levels of markers for early atherosclerosis in anti-citrullinated protein antibodies positive individuals at risk for RA, a cross sectional study.

Helma J HinkemaJohanna WestraSuzanne ArendsElisabeth BrouwerDouwe Johannes Mulder
Published in: Rheumatology international (2024)
Individuals at risk for RA have higher levels of inflammatory markers and VEGF, which suggests that they might also have a risk of higher cardiovascular disease (CVD); however, this does not apply to individuals with ACPA positivity with self-reported joint complaints or without joint complaints only. Therefore, it is important that individuals with RA risk are referred to a rheumatologist to rule in or out arthritis/development of RA and discuss CVD risk.
Keyphrases
  • rheumatoid arthritis
  • cardiovascular disease
  • disease activity
  • ankylosing spondylitis
  • type diabetes
  • endothelial cells
  • risk factors
  • amino acid
  • binding protein
  • idiopathic pulmonary fibrosis