Validation of Myc-Associated Protein X (MAX) regulation in growth hormone secreting and nonfunctional pituitary adenoma.
Douglass W TuckerDhiraj J PangalRobin DuAngad S GogiaAli TafreshiJacob RuzevickKyle T HurthTim TricheAlexander S G MickoJohn D CarptenMark S ShiroishiJohn D CarmichaelSuhn K RhieGabriel ZadaPublished in: PloS one (2023)
GHPA have significantly different DNA methylation and downstream protein expression levels of MAX compared to NFPA. These differences may influence mechanisms involved with cellular proliferation, tumor invasion and hormonal secretion.