Safety and Feasibility of PARP1/2 Imaging with 18F-PARPi in Patients with Head and Neck Cancer.
Heiko SchöderPaula Demétrio De Souza FrançaReiko NakajimaEva BurnaziSheryl RobertsChristian BrandMilan GrkovskiAudrey MauguenMark P DunphyRonald A GhosseinSerge K LyashchenkoJason S LewisJoseph A O'DonoghueIan GanlySnehal G PatelNancy Y LeeThomas ReinerPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Imaging of head and neck cancer with 18F-PARPi is feasible and safe. 18F-PARPi detects primary and metastatic lesions, and retention in tumors is longer than in healthy tissues.