Endothelial Intracellular ANG (Angiogenin) Protects Against Atherosclerosis by Decreasing Endoplasmic Reticulum Stress.

Enyong SuPeng YuBaoli ZhangAnjing ZhangShiyao XieChunyu ZhangSu LiYunzeng ZouMing LiuHong Jiang Jun-Bo Ge

Published in: Arteriosclerosis, thrombosis, and vascular biology (2022)

These results suggest that endothelial intracellular ANG is a novel therapeutic against atherosclerosis and exerts atheroprotective effects via ST3GAL5-mediated ER stress suppression.

Keyphrases

endoplasmic reticulum stress
induced apoptosis
angiotensin ii
endothelial cells
cardiovascular disease
reactive oxygen species
type diabetes