Objective image analysis of real-time three-dimensional intraoperative ultrasound for intrinsic brain tumour surgery.
Sophie J CampVasileios ApostolopoulosVasileios RaptopoulosAmrish MehtaKevin O'NeillMohammed AwadBabar VaqasDavid PetersonFederico RoncaroliDipankar NandiPublished in: Journal of therapeutic ultrasound (2017)
MPB and SD are objective measures reflecting the sensitivity of i3DUS in detecting the presence and extent of intrinsic brain tumours. They indirectly suggest heterogeneity, cellularity and invasiveness, providing information of the nature of the tumour, and also reflect the sensitivity of intraoperative US to detect the presence of residual intrinsic brain tumours. Development of this paradigm will enhance i3DUS use as an adjunct in brain tumour surgery. Optimizing its intraoperative application will impact surgical resection and, hence, patient outcome.