Radiosurgical treatment of arteriovenous malformations in a retrospective study group of 33 children: the importance of radiobiological scores.
Jody Filippo CapitanioPietro PanniAlberto Luigi GallottiCarmen Rosaria GigliottiFrancesco ScomazzoniStefania AcernoAntonella Del VecchioPietro MortiniPublished in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2018)
SRS-GK was safe and gradually effective in children. A prescription dose-like that used in adult population (i.e. > 18 and between 20 and 25 Gy) is essential to achieve obliteration. A PD of 23 Gy and 22 Gy did impact OR, respectively (p = 0.02) and (p = 0.05). FPS and PCI are valuable scores that seem to correlate with the OR also in the pediatric population although further prospective studies are needed to confirm these observations.