Impact of Lipids and Vascular Damage on Early Atherosclerosis in Adolescents with Parental Premature Coronary Artery Disease.

María Del Rocío Martínez-AlvaradoMargarita Torres-TamayoJuan Gabriel Juárez-Rojas Aida X Medina-Urrutia Guillermo C Cardoso-Saldaña Ángel Rene López-Uribe Juan Reyes-Barrera Esteban Jorge-Galarza

Published in: High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension (2024)

Adolescents with a parental history of PCAD had higher IMT values than the control group, primary explained by systolic blood pressure and the parental inheritance. Adolescents with parental history of PCAD and ≥ 3 CRFs exhibited the highest IMT values. Notably, lipids and systolic blood pressure jointly contribute to explain IMT in these adolescents.

Keyphrases

blood pressure
young adults
physical activity
coronary artery disease
hypertensive patients
heart failure
heart rate
left ventricular
cardiovascular disease
gene expression
type diabetes
mitochondrial dna
adipose tissue
cardiovascular events
dna methylation
blood glucose
skeletal muscle
weight loss
glycemic control