Gaining Synthetic Appreciation for the Gedunin ABC Ring System.
David M PinkertonTimothy J Vanden BergPaul V BernhardtCraig M WilliamsPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2017)
Gedunin, first isolated in 1960, displays a remarkable range of biological activity, but has yet to receive dedicated synthetic attention from a ground up construction perspective. Presented herein is a successfully executed approach to the fully functionalized ABC ring system of this challengingly complex natural product.