Urinary Bladder Patch Made with Decellularized Vein Scaffold Seeded with Adipose-Derived Mesenchymal Stem Cells: Model in Rabbits.
Tadeu Ravazi PiovesanaLenize da Silva RodriguesAna Livia de Carvalho BovolatoDiego Noé Rodríguez-SánchezJaqueline de Carvalho RinaldiNilton José Dos SantosJulia Calvi MoriPedro Luiz Toledo de Arruda LourençãoLynn A BirchMatheus BertanhaPublished in: Biomedicines (2022)
Decellularized vena cava scaffolds were able to maintain the integrity of the urinary bladder in the proposed model. In addition, ASCs accelerated the regenerative process development, observed primarily by the new urothelial epithelization and the maturity of mucosa and submucosa fibroblasts.