The association of three DNA repair genes polymorphisms on the frequency of chromosomal alterations detected by fluorescence in situ hybridization.

Fabio Santiago Rafaele Tavares Silvestre Ubirani Barros Otero Marianne Medeiros Tabalipa Marilza de Moura Ribeiro-Carvalho Luciano Rios Scherrer Ahmed Al-Rikabi Thomas Liehr Gilda Alves Maria Helena Faria Ornellas de Souza

Published in: International archives of occupational and environmental health (2021)

The RAD51/G135C polymorphism appears to be related to genome instability in gas station workers. Increasing the knowledge of DNA repair gene variations involved in maintaining genomic stability in GSWs may be crucial for future cancer prevention.

Keyphrases

dna repair
copy number
genome wide
dna damage
genome wide identification
papillary thyroid
dna methylation
dna damage response
healthcare
squamous cell
current status
single molecule
room temperature
genome wide analysis
transcription factor
lymph node metastasis
bioinformatics analysis
gene expression
young adults