Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells.

Weijiang LiuNa ZhouYuanlin LiuWei ZhangXue LiYang WangRongxiu ZhengYi Zhang

Published in: Stem cell research & therapy (2021)

MSCs-Exo-derived miR-223 could attenuate aGvHD in mice through decreasing donor T cell migration. Our results unveil a new role of MSCs-Exo containing miR-223 in the treatment of aGvHD.

Keyphrases

cell proliferation
mesenchymal stem cells
long non coding rna
cell migration
long noncoding rna
umbilical cord
bone marrow
type diabetes
mouse model
respiratory failure
skeletal muscle
drug induced
insulin resistance
combination therapy
smoking cessation