The Burden and Impact of Cough in Patients with Idiopathic Pulmonary Fibrosis: An Analysis of the Prospective Observational PROFILE Study.
Peter SaundersZhe WuWilliam A FahyIain D StewartGauri SainiDavid J F SmithRebecca BraybrookeCarmel StockElisabetta A RenzoniSimon R JohnsonR Gisli JenkinsMaria G BelvisiJaclyn Ann SmithToby M MaherPhilip L MolyneauxPublished in: Annals of the American Thoracic Society (2023)
The burden of cough in IPF is high. Although cough is weakly associated with disease severity at baseline, cough-specific QoL as measured by the LCQ, confers no prognostic value. Cough-specific QoL burden remains relatively stable over time and does not associate with MUC5B promotor polymorphism.