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Identification of Acer2 as a First Susceptibility Gene for Lithium-Induced Nephrogenic Diabetes Insipidus in Mice.

Theun de GrootLena K EbertBirgitte Mønster ChristensenKarolina AndralojcLydie ChevalAlain DoucetCungui MaoRuben BaumgartenBenjamin E LowRoger SandhoffMichael V WilesPeter M T DeenRon Korstanje
Published in: Journal of the American Society of Nephrology : JASN (2019)
We demonstrate that genome-wide association studies in mice can be used successfully to identify susceptibility genes for development of lithium-induced adverse effects. We identified Acer2 as a first susceptibility gene for lithium-induced diabetes insipidus in mice.
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