Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations.

Vidyalakshmi ChandramohanXuhui BaoXin YuScott ParkerCharlotte McDowallYen-Rei YuPatrick HealyAnnick DesjardinsMichael D GunnMatthias GromeierSmita K NairIra H PastanDarell D Bigner

Published in: Journal for immunotherapy of cancer (2019)

These data support the development of D2C7-IT and immune checkpoint blockade combinations for patients with malignant glioma.

Keyphrases

dna damage
electronic health record
cell cycle
cancer therapy
cell proliferation