Utility of cerebrospinal fluid liquid biopsy in distinguishing CNS lymphoma from cerebrospinal infectious/demyelinating diseases.
Chisako IriyamaKenichiro MurateSachiko IbaAkinao OkamotoNaoe GotoHideyuki YamamotoToshiharu KatoKeichiro MiharaTakahiko MiyamaKeiko HattoriRyoko KajiyaMasataka OkamotoYasuaki MizutaniSeiji YamadaTetsuya TsukamotoYuichi HiroseTatsuro MutohHirohisa WatanabeAkihiro TomitaPublished in: Cancer medicine (2023)
These results suggest that mutation analysis using CSF-cfDNA might be useful for differentiating CNSL from CNS infectious/demyelinating diseases and for early detection of CNSL, even in cases where brain biopsy is difficult to perform.