Mutational burden and potential oligogenic model of TBX6-mediated genes in congenital scoliosis.

Yang YangSen ZhaoYuanqiang ZhangShengru WangJiashen ShaoBowen LiuYaqi LiZihui YanYuchen NiuXiaoxin LiLianlei WangYongyu YeXisheng WengZhihong Wunull nullJianguo ZhangNan Wu

Published in: Molecular genetics & genomic medicine (2020)

Our study characterized the mutational spectrum of TBX6-mediated genes, prioritized core candidate genes/variants, and provided insight into a potential oligogenic disease-causing mode in CS.

Keyphrases

genome wide
bioinformatics analysis
genome wide identification
copy number
human health
dna methylation
climate change