Modic Changes of the Cervical and Lumbar Spine and Their Effect on Neck and Back Pain: A Systematic Review and Meta-Analysis.
Mark J LambrechtsTariq Ziad IssaGregory R TociMeghan SchilkenJose A CansecoAlan S HilibrandGregory D SchroederAlexander R VaccaroChristopher K KeplerPublished in: Global spine journal (2022)
Modic changes in the lumbar spine are not associated with clinically significant axial low back pain severity or patient disability. Similar to the lumbar spine, Modic changes in the cervical spine are not associated with symptom severity, but they are associated with pain duration.