Modeling cationic adduction of oligonucleotides using electrospray desorption ionization.
J Michael SuttonMichael G BartlettPublished in: Rapid communications in mass spectrometry : RCM (2020)
Two models are described to understand the physiochemical properties that contribute to the adduction and to provide users a quick mathematical tool to predict the best choice of alkylamine to lower cationic adduction and decrease spectral complexity while enhancing sensitivity.