Atypical Fragility Fractures due to Bony or Soft Tissue Phosphaturic Mesenchymal Tumors: A Report of Two Cases.

Stephanie M Clegg Emily S Eiel Sara Fine Rachel I Gafni Mathew J Most

Published in: Case reports in orthopedics (2023)

TIO is a rare condition presenting with chronic multifocal bone pain, stress fractures, and hypophosphatemia. These two cases highlight that the causative tumor may originate in soft tissue or bone. Furthermore, a high index of suspicion, along with fibroblast growth factor-23 testing and DOTATATE-PET/CT localization, can help with diagnosis and minimize treatment delays.

Keyphrases

soft tissue
pet ct
positron emission tomography
chronic pain
stem cells
pain management
bone marrow
neuropathic pain
quantum dots
bone mineral density
combination therapy
computed tomography
replacement therapy
heat stress