CKD Increases Carbonylation of HDL and Is Associated with Impaired Antiaggregant Properties.

Nans FlorensCatherine CalzadaSandrine LemoineMarie Michèle BouletNicolas GuillotChristophe BarbaJulie RouxFréderic DelolmeAdeline PageJean Michel PouxMaurice LavillePhilippe MoulinLaurent SoulèreFitsum Guebre-EgziabherLaurent JuillardChristophe O Soulage

Published in: Journal of the American Society of Nephrology : JASN (2020)

HDL from CKD rabbits and patients on hemodialysis exhibited an impaired ability to inhibit platelet aggregation, suggesting that altered HDL properties may contribute to the increased cardiovascular risk in this population.

Keyphrases

end stage renal disease
chronic kidney disease
peritoneal dialysis
newly diagnosed
ejection fraction
prognostic factors
patient reported outcomes
patient reported