Pharmacological Interventions for the Prevention and Treatment of Immune Checkpoint Inhibitor-Associated Enterocolitis: A Systematic Review.
Christopher MaJohn K MacDonaldTran M NguyenNiels Vande CasteeleBryan LinggiPavine LefevreYinghong WangBrian G FeaganVipul JairathPublished in: Digestive diseases and sciences (2021)
Current treatment recommendations for ICI-associated enterocolitis are based on very low quality evidence, primarily from case reports and case series. Large-scale prospective cohort studies and RCTs are needed to develop prophylactic and therapeutic treatments to minimize interruption or discontinuation of oncological therapies.