No differential gene expression for CD4+ T cells of MS patients and healthy controls.
Ina S BrorsonAnna ErikssonIngvild S LeikfossElisabeth G CeliusPål Berg-HansenLisa F BarcellosTone BergeHanne F HarboSteffan Daniel BosPublished in: Multiple sclerosis journal - experimental, translational and clinical (2019)
We conclude that CD4+ T cells from multiple sclerosis patients do not show significant differential gene expression. Therefore, gene expression studies of all circulating CD4+ T cells may not result in viable biomarkers. Gene expression studies of more specific subsets of CD4+ T cells remain justified to understand better which CD4+ T cell subsets contribute to multiple sclerosis pathology.