Biomimetic Total Synthesis of the Rubiginosin Meroterpenoids.
Laura BurchillAaron J DayOussama YahiaouiJonathan H GeorgePublished in: Organic letters (2020)
Total synthesis of the Rhododendron meroterpenoids rubiginosins A and G, which both contain unusual 6-6-6-4 ring systems, has been achieved using a bioinspired cascade approach. Stepwise synthesis of these natural products, and the related 6-6-5-4 meroterpenoids fastinoid B and rhodonoid B, from naturally occurring chromene precursors is also reported.
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