Colonization with multi-drug-resistant organisms negatively impacts survival in patients with non-small cell lung cancer.

Jan A StratmannRaphael LackoOlivier BalloShabnam ShaidWolfgang GleiberMaria J G T VehreschildThomas WichelhausClaudia ReinheimerStephan GöttigVolkhard A J KempfPeter KleineSusanne SteraChristian BrandtsMartin SebastianSebastian Koschade

Published in: PloS one (2020)

MDRO colonization is an independent risk factor for inferior OS in patients diagnosed with NSCLC due to a higher rate of fatal infections. Empirical antibiotic treatment approaches should cover formerly detected MDR commensals in cases of (suspected) invasive infections.

Keyphrases

drug resistant
multidrug resistant
end stage renal disease
acinetobacter baumannii
newly diagnosed
ejection fraction
small cell lung cancer
gram negative
peritoneal dialysis
prognostic factors
patient reported outcomes
cystic fibrosis
pseudomonas aeruginosa
combination therapy
tyrosine kinase