Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles.

Helen H N YanHoi Cheong SiuSiu Lun HoSarah S K YueYang GaoWai Yin TsuiDessy ChanApril S ChanJason W H WongAlice H Y ManBernard C H LeeAnnie S Y ChanAnthony K W ChanHo Sang HuiArthur K L CheungWai Lun LawOswens S H LoSiu Tsan YuenHans CleversSuet Yi Leung

Published in: Gut (2020)

These organoid models enriched in EOCRCs with linked genomic data fill a gap in existing CRC models and reveal distinct genetic profiles and novel pathway cooperativity.

Keyphrases

early onset
genome wide
copy number
late onset
dna methylation
single cell
electronic health record
machine learning
deep learning
artificial intelligence