Impaired T helper cell responses in human immunodeficiency virus-exposed uninfected newborns.
Yesenia Brito-PérezRodrigo T Camacho-PachecoNoemi Plazola-CamachoDiana Soriano-BecerrilIrma A Coronado-ZarcoGabriela Arreola-RamírezGabriela González-PérezAlma Herrera-SalazarJulio Flores-GonzálezMextli Y Bermejo-HaroBrenda G Casorla-CervantesIsmael A Soto-LópezJessica Hernández-PinedaClaudia Sandoval-MontesSandra Rodríguez-MartínezRicardo Figueroa DamiánIsmael MancillaPublished in: Immunity, inflammation and disease (2021)
HEU neonates are born with reduced proportions of differentiated Th1 /Th2 /Th17 and CD4+ CD25++ T cells, but the intrinsic abilities of CD4+ T cells to acquire a Th1 profile are not affected by the adverse maternal milieu during development.
Keyphrases
- human immunodeficiency virus
- low birth weight
- hiv infected
- antiretroviral therapy
- gestational age
- hepatitis c virus
- birth weight
- preterm infants
- single cell
- preterm birth
- cell therapy
- pregnant women
- hiv aids
- regulatory t cells
- dendritic cells
- pregnancy outcomes
- stem cells
- body mass index
- mesenchymal stem cells
- immune response
- adverse drug