Electropolymerized molecularly imprinted polypyrrole film for dimethoate sensing: investigation on template removal after the imprinting process.
Marlene ValentinoAnna ImbrianoAngelo TricaseFlavio Della PelleDario CompagnoneEleonora MacchiaLuisa TorsiPaolo BollellaNicoletta DitarantoPublished in: Analytical methods : advancing methods and applications (2023)
The development of ultrasensitive analytical detection methods for organophosphorus pesticides such as dimethoate (DMT) plays a key role in healthy food production. DMT is an inhibitor of acetylcholinesterase (AChE), which can lead to the accumulation of acetylcholine and result in symptoms related to the autonomous and central nervous systems. Herein, we report the first spectroscopic and electrochemical study on template removal after an imprinting process from a polypyrrole-based molecularly imprinted polymer (PPy-MIP) film for the detection of DMT. Several template removal procedures were tested and evaluated using X-ray photoelectron spectroscopy. The most effective procedure was achieved in 100 mM NaOH. The proposed DMT PPy-MIP sensor exhibits a limit of detection of (8 ± 2) × 10 -12 M.
Keyphrases
- molecularly imprinted
- solid phase extraction
- loop mediated isothermal amplification
- label free
- high resolution
- real time pcr
- risk assessment
- molecular docking
- room temperature
- reduced graphene oxide
- single molecule
- gas chromatography
- tandem mass spectrometry
- quantum dots
- ionic liquid
- human health
- molecular dynamics simulations