Genetic analysis reveals the inconsistency of amorpha-4,11-diene synthase, a key enzyme in the artemisinin synthesis pathway, in asteraceae.

Shiyu ChenBaosheng LiaoShuai GuoXiaofeng ShenYing MengYu LiangJiang XuShilin Chen

Published in: Chinese medicine (2023)

This study proved that ADS is a multi-copy gene in Artemisia annua L., and they are not widely distributed in Asteraceae. The data will increase our understanding of the evolutionary selection pressure on ADS genes. The results suggest that ADS genes are subject to strong positive selection internally, and it is possible that they are a recently evolved gene in the Artemisia.

Keyphrases

genome wide
genome wide identification
dna methylation
copy number
genome wide analysis
transcription factor
electronic health record
bioinformatics analysis
big data
gene expression
data analysis
plasmodium falciparum