Incorporating patient-reported outcome data into a predictive calculator for allogeneic hematopoietic cell transplantation recipients.
Bronwen E ShawKathryn E FlynnNaya HeRachel N CusatisAnita D SouzaBetty K HamiltonMary M HorowitzDeborah MattilaRachel PhelanStephanie J LeeRuta BrazauskasPublished in: Cancer (2024)
The authors confirmed the significant, independent association of pre-HCT PRO scores with overall survival, although adding PRO scores to the survival calculator did not improve its performance. They also demonstrated that a single general health question was as accurate as the full measure for predicting survival, an important finding that may reduce respondent burden and promote its inclusion in routine clinical practice. Validation of these findings should be performed.