Prognostic Significance of Immune Cell Populations Identified by Machine Learning in Colorectal Cancer Using Routine Hematoxylin and Eosin-Stained Sections.
Juha P VäyrynenMai Chan LauKoichiro HarukiAndressa Dias CostaJennifer BorowskyMelissa ZhaoKenji FujiyoshiKota ArimaTyler S TwomblyJunko KishikawaSimeng GuSaina AminmozaffariShan-Shan ShiYoshifumi BabaNaohiko AkimotoTomotaka UgaiAnnacarolina F L Da SilvaMingyang SongKana WuAndrew T ChanReiko NishiharaCharles S FuchsJeffrey A MeyerhardtMarios GiannakisShuji OginoJonathan A NowakPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
These findings highlight the potential for machine learning assessment of H&E-stained sections to provide robust, quantitative tumor-immune biomarkers for precision medicine.