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Clinical and Laboratory Features of 184 Italian Pediatric Patients Affected with Selective IgA Deficiency (SIgAD): a Longitudinal Single-Center Study.

Vassilios LougarisAnnamaria SorliniChiara MonfrediniGiulia IngrasciottaAndrea CaravaggioTiziana LorenziniManuela BaronioMarco CattaliniAntonella MeiniLaura RuggeriAnnamaria SalpietroAlba PilottaLivia GrazzaniElena PrandiBarbara FelappiGiulio GualdiAntonella FabianoMaurizio FuotiAlberto RavelliVincenzo VillanacciAnnarosa SoresinaRaffaele BadolatoAlessandro Plebani
Published in: Journal of clinical immunology (2019)
In conclusion, this is the first study to describe a large single-center pediatric cohort of patients affected with SIgAD, revealing that overall most patients do well with regard to infections. Many develop CD, at a rate much higher than the general population. A few normalize their IgA levels. A few progress to CVID. Thus, careful follow-up is suggested to diagnose and treat potential complications earlier for avoiding potential morbidities.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • risk assessment
  • patient reported outcomes
  • risk factors
  • childhood cancer