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On the challenges of predicting treatment response in Hodgkin's Lymphoma using transcriptomic data.

André PatrícioRafael S CostaRui Henriques
Published in: BMC medical genomics (2023)
Taken together, the results reveal improvements for predicting treatment response in HL disease by resorting to sophisticated statistical and ML principles. This work further consolidates the current hypothesis on the structural difficulty of this prognostic task, showing that there is still a considerable gap to be bridged for these technologies to reach the necessary maturity for clinical practice.
Keyphrases
  • clinical practice
  • single cell
  • diffuse large b cell lymphoma
  • electronic health record
  • rna seq
  • genome wide
  • big data
  • machine learning
  • gene expression
  • artificial intelligence
  • dna methylation